The first cells to attach to the basement membrane form the stratum basale.

The stratum basale is a continuous layer of cells.

The stratified squamous epithelium is maintained by cell division within the stratum basale.

Keratinocytes in the stratum basale of the epidermis will multiply through cell division and migrate toward the skin surface.

The deepest layer is the miotic layer, stratum basale producing daughter cells by mitosis.

Merkel cells are also found in the stratum basale with large numbers in touch-sensitive sites such as the fingertips and lips.

Stratum germinativum also called stratum basale.

The blood vessels in the dermis provide nourishment and waste removal to its own cells as well as the Stratum basale of the epidermis.

Stratum basale (basal layer)

It implies increased thickness of the Malpighian layer (stratum basale and stratum spinosum).

Vitamin D is produced in the two innermost strata, the stratum basale and stratum spinosum.

This, in part, is the result of degenerative liquefaction of the stratum basale (bottom cell-layer) of the epidermis.

The stratum basale is the only layer capable of cell division, pushing up cells to replenish the outer layer in a process called terminal differentiation.

The stratum basale is primarily made up of basal keratinocyte cells, which can be considered the stem cells of the epidermis.

After the scab is formed, cells of the stratum basale begin to divide by mitosis and migrate to the edges of the scab.

The term Malpighian layer (stratum malpighi) is usually defined as both the stratum basale and stratum spinosum.

A calcium gradient, with the lowest concentration in the stratum basale and increasing concentrations until the outer stratum granulosum, where it reaches its maximum.

Histologically, molluscum contagiosum is characterized by molluscume bodies in the epidermis above the stratum basale, which consist of large cells with:

The highest concentrations of 7-dehydrocholesterol are found in the epidermal layer of skin, specifically in the stratum basale and stratum spinosum.

Desquamation, the process of cell shedding from the surface of the stratum corneum, balances proliferating keratinocytes that form in the stratum basale.

The larvae migrate in tortuous tunnels in between stratum basale and stratum corneum of the skin, causing serpigenous vesicular lesions.

The stratum spinosum (or spinous layer) is a layer of the epidermis found between the stratum granulosum and stratum basale.

In mammalian skin, they are clear cells found in the stratum basale (at the bottom of sweat duct ridges) of the epidermis approximately 10 m in diameter.

The dermal papillae may be exposed after top layers of the dermis (stratum corneum, stratum granulosum, stratum spinosum and stratum basale) have been removed.

The epidermis consists of five strata; from outer to inner they are: the stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, and stratum basale.