steric hindrance

Steric hindrance however can also be a positive thing.

It is necessary to consider the steric hindrance created by a para-substitution of the 5-aromatic system.

Steric hindrance offered by the groups on nitrogen.

Tertiary substrates do not participate in S2 reactions, because of steric hindrance.

Because complex polymers are large it may create steric hindrance and prevent direct enzyme contact.

The relative stability of these compounds is only partly due to steric hindrance by bulky groups.

However, the two and six hydroxyl group is typically not phosphorylated due to steric hindrance.

Steric hindrance between adjacent groups can also restrict torsional bond angles.

Because of severe steric hindrance, it does not react readily even with simple terminal alkenes.

Like the substrate, steric hindrance affects the nucleophile's strength.

This causes a tension in the molecule, known as steric hindrance, and can substantially increase the reactivity.

Acetylation to yield 15 required high temperatures due to the steric hindrance of the isopropyl group.

Direct union was not considered feasible due to steric hindrance but both joins were made possible by a sulfur contraction method.

Through steric hindrance, the substituents direct the direction of substitution of various groups.

An example of steric effects is steric hindrance.

This peculiarity was attributed to steric hindrance by the bulky isopropyl radicals.

Interestingly this is an example with extreme stereoselectivity due to the severe steric hindrance of an ethano-bridge.

Steric hindrance can be exploited to limit the number of alkylations, as in the t-butylation of 1,4-dimethoxybenzene.

Iodine approaches on the side opposite the chromium tricarbonyl unit due to steric hindrance.

Increased steric hindrance in the transition state as a result of unhindered reactants dramatically lowers the reaction rate.

In the exo-pyridyl isomer on the left, the usual steric hindrance control blocks protonation from above.

The effect of steric hindrance on interaction strength allows this method to resolve (separate) structural isomers.

They occur at a negligible rate in tertiary alkyl halides due to steric hindrance.

It should be borne in mind that in every event, there are particular chemical bonds or steric hindrance, which makes the conformation possible.

However, and dimers are twisted out of a purely cis arrangement due to steric hindrance (Fig. 2 ).