spindle apparatus

It is absolutely required for correct positioning and orientation of mitotic spindle apparatus.

The spindle apparatus of the second meiotic division appears at the time of ovulation.

The spindle apparatus is vaguely ellipsoid in cross section and tapers at the ends.

During metaphase, the chromosomes line up using the spindle apparatus in the middle of the cell along the equatorial plate.

During mitosis, clathrin binds to the spindle apparatus.

This spindle apparatus consists of microtubules, microfilaments and a complex network of various proteins.

This contact between the asbestos fiber and the chromosomes or structural proteins of the spindle apparatus can induce complex abnormalities.

X-rays, for example, may cause aneuploidy by fragmenting the chromosome; it may also target the spindle apparatus.

Brinkley is recognized particularly for contributing to discovery of the attachment of chromosomes to the mitotic spindle apparatus.

In cell biology, spindle apparatus refers to the subcellular structure that segregates chromosomes between daughter cells during cell division.

After replication, the chromosomes (now comprising two chromatids) align at the center of the cell, and are attached to a structure known as the spindle apparatus.

Kinetochores and the spindle apparatus are responsible for the movement of the two sister chromatids to opposite poles of dividing cell nucleus during anaphase.

While the spindle apparatus is composed of hundreds upon hundreds of proteins, the fundamental machinery are the spindle microtubules.

The totality of the contractile ring, the spindle apparatus, microtubules and the dense peripheral material is called the "Fleming body" or "intermediate body".

KIF15 maintains bipolar microtubule spindle apparatus in dividing cells and shares redundant functions with KIF11.

The cellular spindle apparatus includes the spindle microtubules, associated proteins, and any centrosomes or asters present at the spindle poles.

During the process of cell division, the spindle checkpoint prevents separation of the duplicated chromosomes until each chromosome is properly attached to the spindle apparatus.

For example, heterochromatin functions in the organization of chromatin, the cohesive force existing between chromatids, and the tension on chromosomes produced by the spindle apparatus [ 56 57 ] .

More specifically, he added, there is evidence that when an egg lingers in the reproductive tract, the cell's spindle apparatus, which holds the chromosomes, may weaken, causing the chromosomes to fall off.

These models argue that cilia developed from pre-existing components of the eukaryotic cytoskeleton (which has tubulin and dynein- also used for other functions) as an extension of the mitotic spindle apparatus.

MTOCs have two main functions: the organization of eukaryotic flagella and cilia and the organization of the mitotic and meiotic spindle apparatus, which separate the chromosomes during cell division.

Kinesins and cytoplasmic dyneins play essential roles in intracellular transport such as axonal transport and in the formation of the spindle apparatus and the separation of the chromosomes during mitosis and meiosis.

Astral microtubules are not required for the progression of mitosis, but they are required to ensure the fidelity of the process; they are required for the correct positioning and orientation of the mitotic spindle apparatus.

Anaphase lag describes a delayed movement during anaphase, where one homologous chromosome in meiosis or one chromatid in mitosis fails to connect to the spindle apparatus, or is tardily drawn to its pole and fails to be included in the reforming nucleus.