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In 1867 he gave two lectures at the College of Physicians on the sphygmograph, a mechanical device used to measure blood pressure.
A sphygmograph stood upon the table and a gasometer-like engine, which was new to Dr. Ripley, in the corner.
In his early studies Mackenzie used Riva-Rocci's sphygmograph to graphically record the pulse.
Although the instrument was cumbersome and its measurements imprecise, the basic concept of Vierordt's sphygmograph eventually led to the blood pressure cuff that's used today.
The first sphygmograph (pulse writer) for the continuous graphical registration of pulse dates back to Karl von Vierordt in 1854.
More popular, however, was the improved sphygmograph from the French physiologist and pioneer in cinematography Étienne-Jules Marey (1863).
Tonometry is the resurrection of the old sphygmograph technology as it again describes a mechanism for the automatic noninvasive palpation on the arteria radialis.
He was an outstanding student and in 1871 he won the student Pupils' Physical Society prize for his work on the sphygmograph, having been runner-up the previous year.
Besides Marey's sphygmograph, a device developed by the Austrian Samuel von Basch attracted attention and was introduced in Europe in 1880 .
In 1854, he created a device called a sphygmograph, a mechanism consisting of weights and levers used to estimate blood pressure, and considered to be a forerunner of the modern sphygmomanometer.