sodium amide

Here sodium amide is used as the nucleophile yielding 2-aminopyridine.

Sodium amide, also known as sodamide, is a chemical compound.

Sodium amide samples which are yellow or brown in color should be dealt with immediately.

It is also used to make sodium amide.

Another proposed method of synthesis involves reacting 4-chlorobutyronitrile with sodium amide.

In fact, sodium amide is used to deliberately obtain the dehydrohalogenation product.

Alkylating this with 2-dimethylaminoethylchloride in the presence of sodium amide gives chlorphenamine.

In the first step, ammonia is converted to sodium amide:

It is made by reacting ammonia with sodium to make sodium amide.

It can also be made by reacting sodium nitrate with sodium amide.

Normally two equivalents of sodium amide yields the desired alkyne.

As such, sodium amide should always be stored in a tightly closed container, under an atmosphere of nitrogen gas.

Sodium amide is an example.

The sodium amide is produced by reacting solid sodium and liquid ammonia.

The first is from 4-chlorbenzylcyanide, which is reacted with 2-chloropyridine in the presence of sodium amide to form 4-chlorophenyl(2-pyridyl)acetonitrile.

The direct amination of pyridine with sodium amide takes place in liquid ammonia.

Sodium amide may be expected to be corrosive to the skin, eyes and mucous membranes.

It is produced by the reaction of sodium amide with pyridine, the Chichibabin reaction.

The sodium amide is subsequently combined with nitrous oxide:

Alternatively the salt can be obtained by the reaction of sodium nitrate with sodium amide.

Sodium amide will also deprotonate indole and piperidine.

The sodium amide then reacts with nitrous oxide to make sodium azide.

Sodium amide is used in the industrial production of indigo, hydrazine, and sodium cyanide.

In former times, it was prepared by the Castner-Kellner process involving the reaction of sodium amide with carbon at elevated temperatures.

Sodium amide, commonly called sodamide, is the chemical compound with the formula NaNH.