Repeated low-energy PSR treatment is an effective modality for improving dyspigmentation, smoothness, and skin laxity associated with photoaging.

His publications have covered novel treatments for port wine stains, hemangiomas, sun damaged skin, wrinkles, telangiectases, birthmarks, skin laxity, hair removal, tattoo removal and Nevus of Ota removal.

The vertical mattress stitch is most commonly used in anatomic locations which tend to invert, such as the posterior aspect of the neck, the palm of the hand, and sites of greater skin laxity such as closure of lax skin after removing a dermoid cyst.

Leyden et al. conducted a 12-week facial study of GHK-Cu containing face and eye cream, reporting significant improvement of skin laxity, clarity and appearance, reduced fine lines and the depths of wrinkles and increased skin density and thickness comparing to placebo.