single-stranded binding protein

In eukaryotes, these single-stranded binding proteins are a heterotrimeric complex known as replication protein A (RPA).

Unlike protein A it is capable of cleaving the phi X viral DNA in the presence of single-stranded binding protein of the host.

A protein - RPA1L - is the homologue of the bacterial single-stranded binding protein (SSB) and acts in initiating homologous pairing and strand exchange activity.

The lagging strand usually contains longer stretches of single-stranded DNA that is coated with single-stranded binding proteins, which help stabilize the single-stranded templates by preventing a secondary structure formation.