The golden brown pigment forms a large mass in the center of the schizont.

During this process, the organism is known as a meront or schizont.

A cell currently undgergoing schizogony is known as a schizont.

In this stage, many thousands of merozoites are produced in each schizont.

It has been further shown that the gametocytes from one schizont are all male or all female.

During the late schizont stage widespread protein dephosphorylation occurs.

These enter an entrocyte, divide three times to give rise to an octonucleate schizont.

Cytomeres are caused by complex invaginations of the surface of the schizont.

AMA-1 appears to be transported to the merozoite surface close to the time of schizont rupture.

In the late schizont stage it forms globular structures surrounding each budding merozoite.

The protein is mainly expressed during intraerythrocytic schizont stages and localizes to the nuclear region.

The schizont divides and gives rise to eight merozoites which then invade other entrocytes.

This rounded form then matures within the hepatocyte to a schizont containing many merozoites.

Within each schizont are 4-8 merozoites.

Each schizont produces 2-6 merozoites most commonly arranged in fan or cruciform configuration.

Rupture of the schizont consequently causes epithelial cell rupture and death.

The diploid or schizont is multinucleate, and after meiosis fragments to produce new gamonts.

Deletion mutations of this gene result in cell arrest in the late schizont stages.

As schizogony proceeds, the eosinophilic masses approximate forming a deep red border around the developing schizont.

The larger merozoites divide within the lumen of the gut twice giving rise to a four nucleated schizont.

Interestingly, one additional homolog of PfSUB1 was identified among the schizont genes.

SERA6 may also be involved in schizont rupture and merozoite release from the erythrocyte.

Inhibition of CDPK 1 is associated with a block in development at the schizont level.

The schizont divides into four macrogametocytes which then invade the cells of the gut wall where they mature into macrogametes.

Summary: Merozoite trophozoite schizont merozoites.