replication fork

These sequences allow the two replication forks to pass through in only one direction, but not the other.

There is a dramatic increase in processivity at the replication fork.

This is where the replication fork will form.

Topoisomerases are responsible for removing these supercoils ahead of the replication fork.

As a result, the replication forks are constrained to always meet within the termination region of the chromosome.

This arrangement is called the "replication fork trap."

The priming event on the lagging strand establishes a replication fork.

They can cause replication fork stalling and are bypassed by translesion synthesis.

Gyrase is most commonly found upstream of the replication fork, where the supercoils form.

This build-up would form a resistance that would eventually halt the progress of the replication fork.

All other proteins at the replication fork are linked directly or indirectly to DnaB.

Mechanical energy moves the DnaB into the replication fork, physically splitting it in half.

Heading towards the replication fork, the leading strand is synthesized in a continuous fashion, only requiring one primer.

The DNA helicases and polymerases must remain in close contact at the replication fork.

Additionally, to aid termination, the progress of the DNA replication fork must stop or be blocked.

This asymmetry is due the formation of the replication fork and its division into leading and lagging strands.

There are also proteins involved in reassembling histones behind the replication fork to reestablish the nucleosome confirmation.

Interestingly, they are involved in primosome function both at arrested replication forks and at the chromosomal origin.

The leading strand is the template strand that is being replicated in the same direction as the movement of the replication fork.

Electron microscopy studies show that this occurs very quickly, as nucleosomes can be observed forming just a few hundred base pairs after the replication fork.

The replication fork is a structure that forms within the nucleus during DNA replication.

When the replication fork moves around the circle, a structure shaped like the Greek letter theta Ө is formed.

The replication fork forms at a specific point called autonomously replicating sequences (ARS).

Unwinding of DNA at the origin, and synthesis of new strands, forms a replication fork.

Alternatively, the invading 3' end near Chi can prime DNA synthesis and form a replication fork.