Reciprocal translocation: Segments from two different chromosomes have been exchanged.

Some cases are associated with reciprocal translocation between chromosomes or maternal illness.

The use of an unequal reciprocal translocation unbanded, to both mark and split a chromosome region, is illustrated in Figure 7c.

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia.

In addition to the Philadelphia chromosome they also exhibit a second reciprocal translocation between the long arm of chromosome 15 with chromosome 17.

Polymorphic variants and a reciprocal translocation t(6;8)(q26;q13) involving this gene, have been associated with Duane retraction syndrome.

Moreover, if the approximate position on a chromosome is also known, it may be possible to split that region if an appropriate unequal reciprocal translocation is available.

They have been separated in a pair of somatic cell hybrids (TG3 and TK2; 22), each of which carries one of the reciprocal translocation chromosomes.

This is a reciprocal translocation, creating an elongated chromosome 9 (der 9), and a truncated chromosome 22 (the Philadelphia chromosome).

Because of this, genes near the translocation breakpoints on the nonhomologous chromosomes participating in a reciprocal translocation exhibit pseudolinkage: They behave as if they are linked.

If, for example, a reciprocal translocation is fixed in a population, the hybrid produced between this population and one that does not carry the translocation will not have a complete meiosis.

One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centriolin.

Metaphase 1 (M1) is the stage of meiosis used in routine analysis for the establishment of bivalent number, chiasma frequency or position, and for the detection of a chromosomal anomaly such as a reciprocal translocation which can be recognized as a multivalent configuration in the complement.