Ependymomas are believed to arise from radial glial cells.

The first starts out with the expression of Pax6 in radial glial cells found primarily at the ventricular surface.

Tanycytes have been evolutionarily linked to radial glial cells of the central nervous system.

Neuroepithelial cells give rise to radial glial cells early on during embryonic development.

During gliogenesis, radial glial cells differentiate into astrocytes.

While these changes are happening, the cells are also guided to this new layer by radial glial cells.

Many of the neuroepithelial cells also divide into radial glial cells, a similar, but more fate restricted cell.

Radial glial cells.

Indeed, all radial glial cells divide throughout neurogenesis and give rise to the majority of projection neurons in the cerebral cortex.

Tlx is also required for transition from radial glial cells to astrocyte-like neural stem cells.

In the absence of occludin some polarity is still lost and the neuroepithelial cell gives rise to the radial glial cell.

The transition from radial glial cells to postmitotic projection neurons occurs in three steps, each associated with one of the aforementioned transcription factors.

Therefore, nervous tissue develops ladders made of radial glial cells that neurons climb, through the previous layers, to reach their proper destination.

Each layer is formed by radial glial cells located in the ventricular zone or subventricular zone, and then migrate to their final destination.

Studies show that radial glial cells characterized by long radial processes and astroglial properties constitute the majority of precursors during neurogenesis.

HES1 is expressed in both neuroepithelial cells and radial glial cells, both neural stem cells.

Radial glial cells are a subset of astrocytes, which are typically thought of as non-neuronal support cells.

Radial glial cells often divide asymmetrically, producing one new stem cell and one neuronal precursor cell per division.

Theses layers are the last to form during corticogenesis and include pyramidal neurons, astrocytes, Stellates, and radial glial cells.

Being a more fate restricted cell the radial glial cell will either generate postmitotic neurons, intermediate progenitor cells, or astrocytes in gliogenesis.

Pediatric ependymomas are similar in nature to the adult form of ependymoma in that they are thought to arise from radial glial cells lining the ventricular system.

At a later stage of brain development, neuroepithelial cells begin to self renew and give rise to non-stem cell progenitors, such as radial glial cells simultaneously by undergoing asymmetric division.

Tangential migration does not involve interactions with radial glial cells, instead the interneurons migrate perpendicularly through the radial glial cells to reach their final location.

Neuroepithelial cells undergo mitosis generating more neuroepithelial cells, radial glial cells or progenitor cells, the latter two differentiating into either neurons or glial cells.

The new neurons generated by the neuroepithelial cells, progenitors and radial glial cells will not survive unless they are able to integrate into the system by making connections with new neighbors.