Pulmonary interstitial emphysema often resolves gradually and may take 2-3 weeks.

Different treatments have been used to manage pulmonary interstitial emphysema with variable success.

Pulmonary interstitial emphysema is a concern in any of the following diagnosis:

The prevalence of pulmonary interstitial emphysema widely varies with the population studied.

A chest X-ray showed pulmonary interstitial emphysema.

Pulmonary interstitial emphysema is more frequent in premature infants who require mechanical ventilation for severe lung disease.

Infants suffering from pulmonary interstitial emphysema are typically recommended for admission to a neonatal intensive care unit.

Reduction in mortality and the incidence of pneumothorax and pulmonary interstitial emphysema (PIE) has been shown.

Studies reflecting international frequency demonstrated that 2-3% of all infants in NICUs develop pulmonary interstitial emphysema.

The resultant alveolar rupture can lead to pneumothorax, pulmonary interstitial emphysema (PIE) and pneumomediastinum.

In a 1987 study 3% of infants admitted to the neonatal intensive care unit (NICU) developed pulmonary interstitial emphysema.

Pulmonary interstitial emphysema is created when air bursts or ruptures through tissue from the alveoli and bronchioles into the perivascular tissue of the lung.

The Bunnell Life Pulse High-Frequency Ventilator is indicated for use in ventilating critically ill infants with pulmonary interstitial emphysema (PIE).

Pulmonary interstitial emphysema (PIE) is a collection of air outside of the normal air passages in the body and instead is found inside the connective tissue of the peribronchovascular sheaths, interlobular septa, and visceral pleura.