PP1 is one of the major protein phosphatases found in all eukaryotic cells.

Cdc14 was later shown to encode a protein phosphatase.

Sugen also had research programs on protein phosphatases, none of which lead to therapeutics.

Protein phosphatase may refer to one of two enzymes:

This gene encodes a constant regulatory subunit of protein phosphatase 2.

A key regulator of protein phosphatase 2A.

This occurs on its own by hydrolysis, or is mediated by protein phosphatases.

Still another review found evidence that the protein phosphatase 2B (calcineurin) might be involved in susceptibility to schizophrenia.

The toxic effect of microcystins is due to their inhibition of protein phosphatases.

This process can be reversed via the activity of protein phosphatases, which act to dephosphorylate these cation channels.

A homolog of the inhibitor of protein phosphatase 1 has been cloned.

Protein phosphatase 1 can take out these phosphate moieties and make glycogen synthase active.

Laboratory studies with cultured tumor cell lines suggest that this activity may relate to inhibition of protein phosphatase 2A.

Non-transfected U87 cells, or cells transfected with vector alone, did not exhibit protein phosphatase activity above background levels.

A subgroup of proteins identified in this search show similarity to the protein phosphatase 2A regulatory B subunit.

The algal toxin microcystin is also a peptide and is an inhibitor of protein phosphatases.

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily.

Caenorhabditis elegans protein phosphatase ptp-1.

Calcineurin (protein phosphatase 2B)

Ser/Thr-specific protein phosphatases are regulated by their location within the cell and by specific inhibitor proteins.

Insulin causes glycogen synthesis by activating protein phosphatases and producing a decrease in the phosphorylation of these enzymes.

The protein phosphatase Cdc14 dephosphorylates Cdh1 and therefore activates APC.

When the protein has completed its role a protein phosphatase removes the phosphate and the protein reverts to its original state.

Dual-specificity protein phosphatases (DSPs) regulate mitogenic signal transduction and control the cell cycle.

Dual specificity protein phosphatase 4 is an enzyme that in humans is encoded by the DUSP4 gene.