In half the cases there is no history of a primary lesion at all.

Surgery is the therapy of choice for all primary lesions.

It is the first time a skin cancer has developed in that specific area (primary lesion).

The standard approach is complete resection of the primary lesion.

Symptoms depend largely upon the primary lesions giving rise to the condition.

A search for multiple primary lesions should be made in all patients with small bowel carcinoids.

Palliation of symptoms from the primary lesion is of major importance.

These abnormalities, known as 'primary lesions', give rise to osteoarthritic processes.

The primary lesion is known as a 'pintid' and appears, after an incubation period of some months, often on the legs.

The procedure is generally done as an add-on when the primary lesion is removed.

Induction chemoradiation therapy could sterilize the primary lesion.

Patients who later develop primary lesions have poor survival rates compared to those patients whose primaries remain occult, for example 30% versus 60%.

The primary lesion leading to a dominant lethal mutation is a break in the chromosome, in this case, induced by radiation.

Over time, these primary lesions may continue to develop or be modified by regression or trauma, producing "secondary lesions."

The location and treatment of the primary lesion also crucial, as is the removal of any foreign material (bone, dirt, bullets, and so forth).

It had been six years since the primary lesion on her thigh had been diagnosed, then removed along with a few malignant lymph nodes.

Multifocal osteosarcoma classically presents with symmetrical, metaphyseal lesions, and it may be difficult to determine the primary lesion.

If the primary lesion occurs on the sole of the foot it is known as a 'crab-yaw' because of the gait it induces.

Some weeks after the appearance of the primary lesion, a secondary rash is seen, which is equivalent to that seen in secondary syphilis.

Radiation therapy is a logical treatment choice, particularly for patients with primary lesions requiring difficult or extensive surgery (e.g., eyelids, nose, or ears).

Multifocal osteosarcoma is different from osteosarcoma which presents with a clearly delineated primary lesion and limited bone metastasis.

Surgical resection and anastomosis or bypass of obstructing or bleeding primary lesions in selected metastatic cases.

In addition, they did not stain the dendritic cells which are generally prominent in the sentinel lymph nodes after the diagnostic biopsy of a primary lesion.

Tumors without an identifiable primary lesion have been attributed to either spontaneous regression of the primary or metastatic neuroendocrine carcinoma from a clinically occult site.