They may cause pressure necrosis of the nasal septum or lateral wall of nose.

This is called pressure necrosis.

Perforation can happen at the neck from pressure necrosis due to the impacted calculus, or at the fundus.

A growing hematoma causes pressure necrosis of the bone surrounding the hematoma, but only on rare occasions does it cause facial distortion.

Vandenbos and Bowers theorized that pressure necrosis of the soft tissues surrounding the nail due to weight-bearing is the primary cause of ingrowing toenails:

TEF can also occur due to pressure necrosis by a tracheostomy tube in apposition to a nasogastric tube (NGT).

When such persons trim the nail in a curved or rounded fashion instead of straight across, further bulging of soft tissue is allowed, and as the nail grows out, pressure necrosis of soft tissue occurs.

In 2009, Avolio Luigi and Martucciello Giuseppe showed that although ingested nonmagnetic foreign bodies are likely to be passed spontaneously without consequence, ingested magnets (magnetic toys) may attract each other through children's intestinal walls and cause severe damage, such as pressure necrosis, perforation, intestinal fistulas, volvulus, and obstruction.