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A higher incidence of cystic kidney disease is found in the male population and prevalence increases with age.
Gout is frequently present in medullary cystic kidney disease type 2.
Cystic kidney disease in patient or close relatives.
The most common genitourinary condition is cystic kidney disease, but there are many varieties even of this.
It is classified as a medullary cystic kidney disease.
Cystic kidney disease refers to a wide range of hereditary, developmental, and acquired conditions.
Another example of cystic kidney disease is Medullary sponge kidney.
The second group, termed medullary cystic kidney disease, is characterized by autosomal dominant inheritance.
Cystic kidney diseases.
There are at least two types of medullary cystic kidney disease, and kidney failure develops between ages 30 and 70.
Acquired cystic kidney disease (ACKD) usually happens in people who are on dialysis.
These include hydronephrosis, pre-existing arteriovenous fistula in the kidney, cystic kidney disease and small, shrunken kidneys.
Numerous renal cysts are seen in the cystic kidney diseases, which include polycystic kidney disease and medullary sponge kidney.
Medullary cystic kidney disease is an autosomal dominant kidney disorder characterized by cysts in both kidneys and tubulointerstitial sclerosis leading to end-stage renal disease.
Two were known to cause human cystic kidney disease, so we knew we were in the human disease pathway somewhere, but we had no idea what the other genes were'.
Of the cystic kidney diseases, the most common is Polycystic kidney disease; having two prevalent sub-types: autosomal recessive and autosomal dominant polycystic kidney disease.
Autosomal dominant polycystic kidney disease (ADPKD) is the most common of all the hereditary cystic kidney diseases with an incidence of 1 to 2:1,000 live births.
When Zhaoxia Sun, a postdoc in my lab who now has an independent position at Yale Medical School, screened three-day-old fish for cystic kidney disease, she found 12 different genes.
A few rare genetic disorders, including familial juvenile hyperuricemic nephropathy, medullary cystic kidney disease, phosphoribosylpyrophosphate synthetase superactivity, and hypoxanthine-guanine phosphoribosyltransferase deficiency as seen in Lesch-Nyhan syndrome, are complicated by gout.
Acquired Cystic Kidney Disease(National Institute of Diabetes and Digestive and Kidney Diseases) Polycystic Kidney Disease(National Institute of Diabetes and Digestive and Kidney Diseases)
Among the genes identified was an unexpected class of genes which when mutated predispose fish to get cancer, and a set of genes that cause fish to develop cystic kidney and which overlap with genes that cause cystic kidney disease in humans.
Their research leads them to conclude "Our findings suggest that the NPHP genes (NPHP1, NPHP3, NPHP4) involved in the pathogenesis of recessive cystic kidney disease also belong to a common pathway in the primary cilium of kidney cells."
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