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In bone, the plasmacytoma may cause pain or broken bones.
A plasmacytoma in the throat, for example, can make it difficult to swallow.
It is often used as part of the phrase "solitary plasmacytoma".
If only a single tumor is present, the term solitary plasmacytoma is used.
The patient has an isolated plasmacytoma of the bone if the following are found:
Standard treatment options for isolated plasmacytoma of bone include the following:
In some patients, the plasmacytoma may shrink, but not disappear, and the M protein persists.
For multiple myeloma and plasmacytoma, other risk factors include the following:
Standard treatment of isolated plasmacytoma of bone is usually radiation therapy.
If they are associated with an extramedullary (paraspinal) plasmacytoma.
Plasmacytoma of the bone often becomes multiple myeloma.
The rabbit formed a myeloma-like tumor, allowing the isolation of a plasmacytoma cell line, named 240E-1.
Plasmacytoma refers to a malignant plasma cell tumor growing within soft tissue or within the skeleton.
Solitary plasmacytoma and AL amyloidosis.
Plasmacytoma/plasma cell myeloma.
The work up for plasmacytoma includes immunoglobulin electrophoresis (or serum protein electrophoresis) and bone marrow biopsy.
Other blood disorders occur in a significant minority of cases, including Castleman's disease, plasmacytoma and MGUS.
In this type of plasma cellneoplasm, the abnormal plasma cells (myelomacells) collect in one location and form a single tumor, called a plasmacytoma.
A plasmacytoma may form in bone marrow or may be extramedullary (in soft tissues outside of the bone marrow).
Plasmacytoma, multiple myeloma, Waldenström macroglobulinemia and plasma cell leukemia are malignant neoplasms ("cancer") of the plasma cells.
Multiple myeloma is potentially curable when it presents as a solitary plasmacytoma of bone or as an extramedullary plasmacytoma.
Dimopoulos MA, Goldstein J, Fuller L, et al.: Curability of solitary bone plasmacytoma.
Soesan M, Paccagnella A, Chiarion-Sileni V, et al.: Extramedullary plasmacytoma: clinical behaviour and response to treatment.
Strojan P, Soba E, Lamovec J, et al.: Extramedullary plasmacytoma: clinical and histopathologic study.
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with extramedullary plasmacytoma.