Related drugs include phenazocine, dezocine, cyclazocine and several chemicals used in research on the central nervous system.

These include cyclazocine, pentazocine, and phenazocine.

Cyclazocine is a mixed opioid agonist/antagonist related to dezocine, pentazocine and phenazocine.

Phenazocine appears to be a much stronger analgesic with fewer side effects than pentazocine, probably due to a more favorable μ/κ binding ratio.

Effects of phenazocine include analgesia and euphoria, also may include dysphoria and hallucinations at high doses, most likely due to action at κ-opioid and σ receptors.

Phenazocine was once widely used, and was mainly supplied as 5mg tablets of the hydrobromide salt for sublingual use (Narphen, Prinadol and other names), but its use was discontinued in the United Kingdom in 2001.