Peripheral artery occlusive disease (the most severe form of which is gangrene)

Peripheral artery occlusive disease (PAOD)

Atheroma in arm, or more often in leg arteries, which produces decreased blood flow is called peripheral artery occlusive disease (PAOD).

Peripheral artery occlusive disease is commonly divided in the Fontaine stages, introduced by René Fontaine in 1954 for ischemia:

Antithrombotic therapy for peripheral artery occlusive disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

Diltiazem is relatively contraindicated in the presence of sick sinus syndrome, atrioventricular node conduction disturbances, bradycardia, impaired left ventricle function, peripheral artery occlusive disease, and chronic obstructive pulmonary disease.

Atherosclerotic restriction to the arterial supply in peripheral artery occlusive disease may result in painful arterial ulcers of the ankle and foot, or give rise of gangrene of the toes and foot.

The North American Thrombosis Forum's (NATF) mission is to focus on unmet needs and issues related to thrombosis and cardiovascular disease such as deep vein thrombosis, pulmonary embolism, myocardial infarction, peripheral artery occlusive disease and stroke.