Surgery may be necessary if your symptoms do not improve with medicines or you have complications such as bleeding or perforation of the intestine.

Perforation of the intestines results in the potential for bacterial contamination of the abdominal cavity (a condition known as peritonitis).

Bleeding internally Perforation of the intestine and peritonitis Bowel obstruction Call 911 if you:

Watery diarrhea, up to 15 times each day Severe abdominal pain Loss of appetite Fever Blood or pus in the stool Weight loss In some cases, C. diff infection can lead to a perforation of the intestines, which can be fatal if not treated immediately.