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The large amounts of ouabain used by the Indians proved toxic to their prey.
Ouabain seems to be normally present in the body in one 10-millionth the amount of sodium, the researchers said.
However, a high dose of ouabain can lead to ventricular tachycardia.
Post asked whether the enzyme was inhibited by ouabain.
Three minutes were all the ouabain required.
The Galápagos tortoise, however, is immune to the effects of ouabain darts.
The researchers said they believe that ouabain slows the pumping of sodium out of the cells.
Several additional observations led to the view that the circulating ouabain in humans was an endogenous hormone.
Drugs such as ouabain and digoxin are cardiac glycosides.
It is the aglycone of k-strophanthin, an analogue of ouabain.
In 1991, a potent sodium pump inhibitor was isolated from the human circulation and identified as ouabain.
(The drugs were later publically identified as digitalis and ouabain.)
It is however, just like its derivate oleandrigenin, a more potent glycoside than ouabain.
Ouabain increases the force of muscle contractions in the heart, leading to a loss of coordination, collapse, and sometimes death.
This plant contains ouabain, which is a cardiac glycoside, oleander, and milkweeds.
There is compelling analytical evidence that ouabain is synthesized in the adrenal gland.
Further, secretion is not equivalent to biosynthesis; most all tissues sequester ouabain from the circulation.
When such tissues are removed from the circulation they secrete ouabain but this phenomenon, by itself, is not proof of biosynthesis.
Extracts containing ouabain have long been used by Somali tribesmen and other groups to poison hunting arrows.
A sufficiently concentrated ouabain dart can bring down a Hippopotamus probably as the result of respiratory and/or cardiac arrest.
The mode of action and significance of physiological levels of endogenous ouabain are under active investigation.
Its sap contains the deadly cardiotoxic glycoside ouabain.
However, this possibility has been excluded by the synthesis of the 11 epimer and the demonstration that it has different chromatographic behavior from ouabain.
The positive properties of ouabain regarding the prophylaxis and treatment of these two indications are documented by a clutch of studies.
Effect of ouabain upon erythrocyte membrane adenosine triphosphatase in Duchenne muscular dystrophy.