This is usually a result of osmotic diuresis.

A large part of the shifted extracellular potassium would have been lost in urine because of osmotic diuresis.

This causes an osmotic diuresis which results in a loss of electrolytes i.e.: Na+, K+.

Glycosuria leads to excessive water loss into the urine with resultant dehydration, a process called osmotic diuresis.

Hyperalimentation can also cause an osmotic diuresis due to an increased load of urea from protein catabolism.

The most common cause of polyuria in both adults and children is uncontrolled diabetes mellitus, causing an osmotic diuresis.

Osmotic diuresis is increased urination caused by the presence of certain substances in the small tubes of the kidneys.

Dehydration results following the osmotic movement of water into urine (Osmotic diuresis), exacerbating the acidosis.

Osmotic diuresis results in dehydration from polyuria and the classic polydipsia (excessive thirst) associated with DM.

Acute hyperglycemia involving glucose levels that are extremely high is a medical emergency and can rapidly produce serious complications (such as fluid loss through osmotic diuresis).

Third, spacing of fluids such as peritonitis, osmotic diuresis, or low aldosterone states such as Addisons Disease.

High glucose levels spill over into the urine, taking water and solutes (such as sodium and potassium) along with it in a process known as osmotic diuresis.

Osmotic diuresis of glucose will cause further removal of water and electrolytes from the blood resulting in potentially fatal dehydration, tachycardia and hypotension.

Sodium, chloride, potassium are excreted in Osmotic diuresis, originating from Diabetes Mellitus (DM).

Prophylactic measures to reduce the risk of renal failure may include low-dose dopamine, vigorous hydration with crystalloid solutions, and osmotic diuresis with mannitol.

Polydipsia and polyuria occur when blood glucose levels rise high enough to result in excretion of excess glucose via the kidneys (glycosuria), producing osmotic diuresis.

This leads to polyuria (excessive urination, an osmotic diuresis), which, in turn, leads to volume depletion and hemoconcentration that causes a further increase in blood glucose level.

None of these patients received loop diuretics and, indeed, the authors have argued that hydration alone may have been sufficient to produce many of salutary effects of the osmotic diuresis [ 7].

Because sodium and calcium clearance are closely linked during osmotic diuresis, loop diuretics will depress the proximal tubular resorptive mechanisms for calcium, increasing calcium excretion to 400 to 800 mg per day.