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Of particular interest, the loss of orbital fat was unilateral in patients who used bimatoprost on only one eye.
With age the septum may weaken, and as a result orbital fat may herniate forwards.
Healing of these injuries occurs naturally by scarring of dorsal orbital fat to the sclera.
It can range from a diffuse inflammatory process to a more localized inflammation of muscle, lacrimal gland or orbital fat.
Thyroid eye disease is an inflammatory condition, which affects the orbital contents including the extraocular muscles and orbital fat.
The orbital fat or the stretching of the nerve due to increased orbital volume may also lead to optic nerve damage.
Aging causes laxity and downward shift of eyelid tissues and atrophy of the orbital fat.
Reductions in orbital fat (i.e., fat around the eye) have been observed in patients using bimatoprost as glaucoma therapy.
The thyroid-stimulating hormone receptor (TSH-R) is an antigen found in orbital fat and connective tissue, and is a target for autoimmune assault.
If the infection moves past the septum, into the orbital fat or the extraocular muscles that move the eye, it becomes a medical emergency, an orbital cellulitis, also called a septal cellulitis.
Enophthalmos is the posterior displacement of the eyeball within the orbit due to changes in the volume of the orbit (bone) relative to its contents (the eyeball and orbital fat), or loss of function of the orbitalis muscle.
The fascia bulbi (also known as the capsule of Ténon and the bulbar sheath) is a thin membrane which envelops the eyeball from the optic nerve to the limbus, separating it from the orbital fat and forming a socket in which it moves.