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Research was undertaken and approximately 90% of nitrosamine compounds were deemed to be carcinogenic.
No satisfactory explanation has been found for this spontaneous decline although changes in the nitrosamine content of foods may be one factor.
Additionally, manufacturers may include alpha-tocopherol (vitamin E) to further inhibit nitrosamine production.
No nitrosamine is formed in stools, even after addition of a secondary amine or nitrite.
The nitrosonium cation then reacts with an amine to produce nitrosamine.
All of them inhibit nitrosamine formation.
The rearrangement reaction takes place by reacting the nitrosamine precursor with hydrochloric acid.
He contributed to studies on the carcinogenicity of 4-nitroquinoline-N-oxide derivatives, the production of plant tumors by a nitrosamine.
Tobacco smoke also contains nitrosamine cancer-causing agents.
There are also rules about adding ascorbic acid or related compounds to meat, in order to inhibit nitrosamine formation.
Vitamin C, beyond its antioxidant muscle, also inhibits the creation of nitrosamine in the stomach, a potentially dangerous carcinogen.
An issue that I know is of concern is that of aspartame, nicin and nitrosamine.
Nevertheless, there are advanced amines in testing with little to no vapor pressure to avoid these amine- and consecutive nitrosamine emissions.
Nitrosamine occurs in latex products such as balloons, and in many foods and other consumables.
Nitrosamine is a carcinogenic substance which is derived from, and produced by, nitrates and nitrites.
The company says it has pushed the farmers from whom it buys tobacco to cure it somewhat differently so that the nitrosamine levels are lower.
"Snus are made with a special process to help control nitrosamine levels," Hecht tells WebMD.
Vitamin C may prevent some cancers by inhibiting the formation of mutagenic N-nitroso compounds (nitrosamine).
We have also asked EFSA to evaluate nicin and nitrosamine, two antimicrobial agents, as a matter of priority.
Alpha-tocopherol, ascorbic acid, and erythorbic acid all inhibit nitrosamine production by their oxidation-reduction properties.
NNK (nicotine-derived nitrosamine ketone)
Nitrosation is adding a nitrosonium ion NO to an amine -NH leading to a nitrosamine.
The next intermediate is the stable nitrosamine with goes on to lose water forming the diazonium salt which then reacts with the vinyl group in the ring-closing step.
The Fischer-Hepp rearrangement is a rearrangement reaction in which an aromatic N-nitroso or nitrosamine converts to a carbon nitroso compound:
N-Nitrosonornicotine (NNN) is a nitrosamine found in tobacco that has been classified by the IARC as a Group 1 carcinogen.