microglial cell

In the brain, they are mainly expressed by microglial cells, where their role remains unclear.

The following are prominent examples of microglial cells' role in neurodegenerative disorders.

The only brain cell type that is "productively" infected with the virus are microglial cells.

Microglial cells are activated via various pro-inflammatory cytokines (some discussed above).

Perlecan expression was traced to microglial cells in the hippocampus and astrocytes.

Microglial cells are extremely plastic, and undergo a variety of structural changes based on their location and current role.

In this manner microglial cells also act as "housekeepers" cleaning up random cellular debris.

During developmental wiring of the brain, microglial cells play a large role removing unwanted excess cellular matter.

In addition to being very sensitive to small changes in their environment, each microglial cell also physically surveys its domain on a regular basis.

It is also found in the kidney, optical choroid, and parts of the central nervous system such the brain and microglial cells.

Gitter cells are the eventual result of microglial cell's phagocytosis of infectious material.

Microglial cells are small relative to macroglial cells, with changing shapes and oblong nuclei.

As mentioned above the cytokine IFN-γ can be used to activate microglial cells.

This suggests that chemical factors that are released from microglial cells are contributing to neuronal loss.

Strong LHR expression in microglial cells in the brain cortex is of particular interest.

During repair and development, myeloid recruitment and differentiation into microglial cells is highly accelerated to accomplish these tasks.

Once the microglial cell is "full" it stops phagocytic activity and changes into a relatively non-reactive gitter cell.

Macrophages and microglial cells are the cells infected by HIV in the central nervous system.

However, not all neuronal cells are immunopositive for Kctd7, and expression is not seen in astrocytes or microglial cells.

The cytokine factors then bind with endothelial receptors on vessel walls, or interact with local microglial cells.

Franz Nissl and F. Robertson first described microglial cells during their histology experiments.

The CSF1 receptor protein primarily functions in regulation, survival, proliferation, and differentiation of microglial cells.

This may explain why the majority of ameboid microglial cells are found within the "fountains of microglia" in the cerebral cortex.

It has been found that "active microglial cells in HSV encephalitis patients do persist for more than 12 months after antiviral treatment."

Microglial cells differentiate in the bone marrow from hematopoietic stem cells, the progenitors of all blood cells.