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Matrix metalloproteinase inhibitors that may be antiangiogenic are batimastat and marimastat.
It acted as a broad-spectrum matrix metalloproteinase inhibitor.
GM6001 also known as galardin or ilomastat is a broad-spectrum matrix metalloproteinase inhibitor.
Exogenous matrix metalloproteinase inhibitors that were developed as anticancer drugs include batimastat and marimastat.
A related class of drugs, known as matrix metalloproteinase inhibitors, which disable an enzyme that tumors use to invade surrounding tissues, is also advancing.
Much attention has been focused recently on a group of drugs called matrix metalloproteinase inhibitors, which disable an enzyme that tumors use to invade surrounding tissues.
Metalloproteinase inhibitor 3 is an protein that in humans is encoded by the TIMP3 gene.
One of these proteins from Streptomyces nigrescens, is the well characterised metalloproteinase inhibitor SMPI.
A matrix metalloproteinase inhibitor (MMPI) inhibits matrix metalloproteinases.
The metalloproteinase inhibitors (MPIs) can prevent unwanted proteolysis by denaturing their target proteases through non-competitive inhibition at an allosteric site.
A secondary ingredient in the cream is Metalloproteinase inhibitor (MPI) which, Dr. Brown said, costs $25,000 a gram and works to block a collagen-destroying enzyme.
It acts as a matrix metalloproteinase inhibitor (MMPI) by mimicking natural MMPI peptides.
The tetracycline antibiotic Doxycycline is currently being investigated for use as a potential drug in the prevention of aortic aneurysm due to its metalloproteinase inhibitor and collagen stabilising properties.
Under all circumstances, stimulated sAPP α shedding was completely blocked using TNFα protease inhibitor 2, a standard α-secretase/metalloproteinase inhibitor (Figure 2).