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In the merozoite the protein relocalizes to the sub nuclear region.
A merozoite is a "daughter cell" of a protozoan.
After invasion by the merozoite these proteins become dephosphorylated.
It also moves from the rhoptry neck to the moving junction during merozoite invasion.
This data also suggest that the conoid was lost twice independently in all stages with the exception of the merozoite.
In the late schizont stage it forms globular structures surrounding each budding merozoite.
This form is the merozoite.
Within the erythrocytes the merozoite grow first to a ring-shaped form and then to a larger trophozoite form.
Following schizont rupture, the distribution of PK66 changes in a coordinate manner associated with merozoite invasion.
Prior to rupture, the protein is concentrated at the apical end, following which it distributes itself entirely across the surface of the free merozoite.
SERA6 may also be involved in schizont rupture and merozoite release from the erythrocyte.
The merozoite enters a gap formed in the host cell's brush border and then becomes enclosed by extensions of the host cell wall.
After entering the erythrocyte, the merozoite lose one of their membranes, the apical rings, conoid and the rhopteries.
These schizonts then undergo cellular segmentation and differentiation to form roughly 16-18 merozoite cells in the erythrocyte.
The P2 protein is exported to the infected erythrocyte surface at 30 hrs post merozoite invasion, concomitant with extensive oligomerization.
Surfin 4.1 - a type I transmembrane protein located on the merozoite surface - is responsible for reversible adherence to the erythrocyte before invasion.
Eighteen ORFs, identical or homologous to proteins associated with the merozoite surface, were present among the schizont-enriched genes.
In the case of malaria, the sporozoite and merozoite stages of Plasmodium elicit the antibody response which leads to premunition.
The calcium dependent protein kinase PfCDPK5 which is expressed in the merozoite is essential for this process.
A merozoite surface protein is a protein molecule taken from the skin, or surface, of a merozoite.
These fragments become covalently linked to the C-terminal 18 kDa fragment via disulfide bonding and attach to the merozoite surface.
Life cycle: merozoite trophozoites schizont merozoite.
Trophozoite and merozoite growth ruptures the host erythrocyte, leading to the release of vermicules, the infectious parasitic bodies, which rapidly spread the protozoa throughout the blood.
In one study, of the 2,415 proteins were identified in four stages(sporozoite, merozoite, trophozoite, gametocyte), representing 46% of the theoretical number of proteins.
Apical Sushi Protein and Rhoptry Neck protein 2 are released early following the formation of the tight junction between the merozoite and the erythrocyte.