The second area that did not receive any virus from the prostate is the medial preoptic area.

Appetitive behaviors are also partly controlled by medial preoptic area as aromatase-knockout mice show deficits in sexual motivation.

Lesions of the rostral part of medial preoptic area also diminish preference for female by male rats.

The medial preoptic area of the brain is considered to control the expression of both male copulation and male appetitive sexual behavior.

However, appetitive behaviors are disrupted by the lesions in rostral part rather than caudal part of medial preoptic area.

Approximately equal numbers of bladder and prostate neurons were found in all locations except for Barrington's nucleus and the medial preoptic area.

The volume of SDN in medial preoptic area is modified by hormones, among which testosterone is proved to be of much importance.

Evidence shows that SDN in medial preoptic area is not the prerequisite for the expression of male-typical sexual behaviour and sexual partner preferences in females.

Bilateral damage to SDN in the medial preoptic area in male ferrets causes the change of males from male-typical preference to female-typical preference.

Also, the nucleus raphe pallidus receives afferents from the medial preoptic area, median preoptic nucleus and lateral paragigantocellular reticular nuclei.

Sexually dimorphic nucleus (SDN) is a cluster of cells located in the medial preoptic area of hypothalamus of the brain that is believed to be related to sexual behavior in animals.

Labeled neurons were found in the raphe nuclei, gigantocellular reticular nucleus, A5 adrenergic nucleus, locus coeruleus, sub coeruleus, Barrington's nucleus, periaquaductal gray, red nucleus, paraventricular nucleus, lateral thalamus, and medial preoptic area.