mean dose

'Note:"' 1 ppm of population is about 5 standard deviations away from the mean dose.

Rather than ignore the potential impact of dose on the outcome measure, we assigned the mean dose reported for the entire study population to each individual within a particular study.

When salmeterol was compared with salbutamol the geometric mean dose equivalence for FEV 1, heart rate, plasma potassium concentration, QTc interval, and tremor amplitude ranged from 3.1 to 12.6 (table II).

Current supplemental guidelines recommend doses of phytosterols in the 1.6-3.0 grams per day range (Health Canada, EFSA, ATP III,FDA) with a recent meta-analysis demonstrating an 8.8% reduction in LDL-cholesterol at a mean dose of 2.15 gram per day.