From a biomechanical point of view, the role of the macula flava is very important.

Some stellate cells were present in the macula flava, but started to show some signs of degeneration.

In the infant, many fibrous components were seen to extend from the macula flava towards the Reinke's space.

The macula flava is composed of fibroblasts, ground substances, elastic and collagenous fibers.

Posteriorly, this vibratory portion is connected to the vocal process of the arytenoid cartilage by the posterior macula flava.

Hirano and Sato studies suggested that the macula flava is responsible for the synthesis of the fibrous components of the VF.

The macula flava in newborn vocal folds is important for the growth and development of the vocal ligament and layered structure of the vocal folds.

Age-related changes in the macula flava influence the fibrous components of the vocal folds and are partially responsible for the differences in the acoustics of the adult and aged voice.

The vibratory portion of the vocal fold in the anterior glottis is connected to the thyroid cartilage anteriorly by the macula flava and anterior commissure tendon, or Broyle's ligament.