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However, patients with lymphoblastic lymphoma had a much inferior outcome.
Lymphoblastic lymphoma within the mediastinum is not considered low-stage disease.
Treatment of adult lymphoblastic lymphoma may include the following:
The incidence of lymphoblastic lymphoma remains relatively constant across ages for both males and females.
It can also be demonstrated in small lymphocytic and lymphoblastic lymphomas, although more specific markers are available for these conditions.
For recurrent or refractory lymphoblastic lymphoma, survival in the literature ranges from 10% to 40%.
Lymphoblastic lymphoma makes up approximately 20% of childhood NHL.
This drug may also be used to treat Crohn's disease, ulcerative colitis, and lymphoblastic lymphoma.
Treatment options for recurrent lymphoblastic lymphoma include:
Lymphoblastic lymphoma.
Low-stage lymphoblastic lymphoma may occur in lymph nodes, bone, and subcutaneous tissue.
Lymphoblastic lymphoma (precursor T-cell) is a very aggressive form of NHL.
However, one study demonstrated that loss of heterozygosity on chromosome 6q in T-cell lymphoblastic lymphoma patients was associated with an increased risk of relapse.
Patients with high-stage (stage III or IV) lymphoblastic lymphoma have long-term survival rates higher than 80%.
It is sometimes additionally classified as a lymphoma, as designated Precursor T-cell lymphoblastic lymphoma.
Nelarabine is used to treat T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.
All current therapies for advanced-stage lymphoblastic lymphoma have been derived from regimens designed for the treatment of acute lymphoblastic leukemia.
Lymphoblastic lymphoma is a very aggressive form of non-Hodgkin lymphoma (NHL), which often occurs in young patients, but not exclusively.
Lymphoblastic lymphoma is a rare type of non-Hodgkin lymphoma, a result of abnormal adaptive immune cells, typically T-cells.
Mediastinal adenopathy, however, is a prominent feature of lymphoblastic lymphoma and primary mediastinal B-cell lymphoma, entities primarily found in young adults.
It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides, but is frequently lost in other T-cell neoplasms.
For low-stage lymphoblastic lymphoma (stage I/II disease), about 60% of patients can achieve long-term DFS with short, pulsed chemotherapy.
Morel P, Lepage E, Brice P, et al.: Prognosis and treatment of lymphoblastic lymphoma in adults: a report on 80 patients.
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with adult lymphoblastic lymphoma.
About 1,600 new cases are diagnosed each year in the United States of the cancers, T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.