What effect do diet and drugs have on lipid rafts?

GM1 gangliosides are found in lipid rafts on the cell surface.

Arguments against the existence of lipid rafts include the following:

When the N-terminus dissociates it can be found in lipid rafts.

Gamma secretase activity has also been associated with lipid rafts.

One lipid-cholesterol system that has recently been studied intently is the lipid raft.

What effect do proteins located at raft boundaries have on lipid rafts?

A second argument questions the effectiveness of the experimental design when disrupting lipid rafts.

This phase has been related to lipid rafts that may exist in plasma membranes.

What is the physiological function of lipid rafts?

Recently, lipid rafts have been speculated to be involved in the cascade of cell apoptosis.

In fact, researchers have hypothesized that the lipid rafts can be extracted from a plasma membrane.

In the plasma membrane, one approach of compartmentalization utilizes lipid rafts.

Manipulation of cholesterol is one of the most widely used techniques for studying lipid rafts.

The presence of specialized structures named "lipid rafts" in the erythrocyte membrane have been described by recent studies.

Research has shown that lipid rafts generally contain 3 to 5-fold the amount of cholesterol found in the surrounding bilayer.

Pike and Miller discuss potential pitfalls of using cholesterol depletion to determine lipid raft function.

Cholesterol, a molecule that is enriched in lipid rafts, has a shorter hydrophobic length.

FRET is also used to study lipid rafts in cell membranes.

The shedding is lipid raft dependent.

Lipid rafts and caveolae are examples of cholesterol-enriched microdomains in the cell membrane.

Lipid raft formation brings receptor proteins in close proximity with high concentrations of second messenger molecules.

It is an important lipid for biophysical experiments and has been used to study various subjects such as lipid rafts.

In order to illustrate these principles, detailed examples of signalling pathways that involve lipid rafts are described below.

One key difference between lipid rafts and the plasma membranes from which they are derived is lipid composition.