Such a "knock-in" approach would, in effect, significantly increase the repertoire of regulatory elements available to drive transgene expression.

You need to get your tools ready -a vacuum, hammer drill, wall plug or a knock-in nail.

The instruments used are knock-in trigger forward option contracts and forward foreign exchange contracts.

A knock-in option is an option that only comes into being when a pre-specified spot level is reached.

Genetic interactions (epistasis) can often confound simple interpretations of such "knock-out" or "knock-in" studies.

The other research assistant will generate two knock-in transgenic mouse lines and contribute to an expression survey of guidance molecules and their receptors.

Hammer-in insert nuts, also known as knock-in nuts, are lined with barbs and are hammered in.

In an era of ankle-high boots and knock-in sprigs, Trebilcock served a seven-year apprenticeship before taking over as the club's No.

In his experiments, transgenic animals that have 'knock-in' genes or 'knockout' genes are used to provide useful animal models for the development of gene therapies.

Finally, we are creating inducible and knock-in mouse models to test the effect of systemic activation of pRb on development, ageing and cancer.

By breeding these "knock-in" transgenic mice, they generated heterozygous females with both an M cone and an L cone.

Using knock-in mice, Dr. Kitamoto evaluated infection using FDC assay.

Dr. Tetsuyuki Kitamoto explained that he had created two types of humanized mice: transgenic mice and knock-in mice.

A second methodology for creating a humanized mouse involves knock-in mouse technology, using homologous recombination technology to exchange the open reading frame from a mouse form to a human form.

Transgenic and knock-in systems both have short incubation periods, but transgenic mice do not accumulate splenic FDC, whereas knock-in mice do.

Genetic vectors will be able to more effectively knock-out or knock-in specific gene sequences for DNA repair, and methods to regulate and maintain stability of gene expression will also be developed.

Activation-dependent T cell revision process is part of peripheral tolerance mechanisms if the new TCR specificity looses its autoractive specificity as described in mouse transgenic and knock-in mouse models or in self-reactive conventional T cells in mouse or man.

They would be opposite of the vanilla structure: the conversion price would act as a knock-in short call option: as the stock price drops below the conversion price the investor would start to be exposed the underlying stock performance and no longer able to redeem at par its bond.

Now, with a grant from The March of Dimes Foundation, Mills' team is the first to make a "knock-in" mouse model of EEC in which they replaced the normal p63 gene with a version bearing the single-letter mutation that causes EEC in people.

In a 2012 study conducted by the University of Texas Southwestern Medical Center in Dallas, mutant mice (with a knock-in mutation of BCL2 phosphorylation sites to produce progeny that showed normal levels of basal autophagy yet were deficient in stress-induced autophagy) were tested to challenge this theory.