iridocorneal angle

This view of the iridocorneal angle provides information in several ways:

In 1898 he was the first physician to study the iridocorneal angle in a living human.

In studied mammalian species, iridocorneal angle development is incomplete at birth.

In most eyes, the iridocorneal angle was abnormal.

This indicates that these pro-apoptotic molecules are not required for normal iridocorneal angle development.

The iridocorneal angle is initially occupied by a densely packed mass of mesenchymal cells.

Iridocorneal angle development is somewhat variable both temporally and spatially within a single eye and between eyes.

Iridocorneal angle morphology was interpreted from plastic sections.

Whether cell death or atrophy occurs during TM and iridocorneal angle development remains controversial.

There was a clear separation between the developing iris and cornea, the first appearance of the iridocorneal angle recess (Figure 2D).

After the migrating mesenchymal cells reach the anterior margin of the developing optic cup they must form the tissues of the iridocorneal angle.

Based on these observations, we conclude that neither apoptosis nor necrosis are important mechanisms in development of the mouse TM and iridocorneal angle.

To investigate the consequences of functionally halving Bmp4 gene dosage on iridocorneal angle development in more detail, we used transmission electron microscopy.

The steeper curvature of this goniolens' exterior surface optically eliminates the total internal reflection problem and allows a view of the iridocorneal angle.

Gonioscopy indicates the angular width of the iridocorneal angle by the number of ocular structures visible above the rim of the iris.

The molecular mechanisms responsible for normal or abnormal development of the iridocorneal angle, its structures, and increased resistance to aqueous drainage in glaucoma are not well defined.

Our data suggest that IOP is normal even when 50% of the iridocorneal angle around the circumference of the eye is severely abnormal.

Its four symmetrical prisms allow visualisation of the iridocorneal angle in four quadrants of the eye simultaneously, and works well with a slit lamp.

Anterior synechiae: Anterior synechiae are simply stands of the iris attaching to the iridocorneal angle or surrounding tissue.

The demonstration of cell death in a SD strain of rats has fueled the debate about mechanisms of iridocorneal angle development [ 18].

The iridocorneal junction is located in a region known as the iridocorneal angle because of the aqueous filled angular recess between the iris root and cornea.

Due to these previous reports, we will focus on the formation of the iridocorneal angle structures (see figure 2Afor location) with brief mention of the adjacent iris and cornea.

Depending on the mouse and ocular location, the iridocorneal angle and its structures typically reached their mature state by P35 to P42 (compare Figure 3Cand 3D).

The iridocorneal angle contains the ocular drainage structures (trabecular meshwork and Schlemm's canal) and is located at the junction of the iris and cornea.

Electron microscopy To further understand iridocorneal angle development, we analyzed stages involving significant changes in the TM and SC using EM.