CT of invasive pulmonary aspergillosis in children with cancer.

Radiologic examination plays an important role in diagnosis and follow-up of invasive pulmonary aspergillosis.

Invasive pulmonary aspergillosis is the most common presentation among HIV-infected children (223,225,226).

Invasive pulmonary aspergillosis commonly associated with fever, cough, dyspnea, and pleuritic pain.

Immunosuppressed individuals are susceptible to invasive A. fumigatus infection, which most commonly manifests as invasive pulmonary aspergillosis.

Invasive pulmonary aspergillosis transformed into fatal mucous impaction by immune reconstitution in an AIDS patient.

Computed tomography (CT) of the chest can be used to identify the halo sign, a macronodule surrounded by a perimeter of ground-glass opacity, which is an early sign of invasive pulmonary aspergillosis (232).