It would be extremely difficult to insufflate such a quantity, as tolerance would likely develop before the 12-gram nasal intake could be completed.

The body would begin to develop tolerance to 5-MeO-DMT before being able to insufflate all 12 grams of beans.

It's likely to be impossible to insufflate the 25 grams of beans required to reach the active dose of DMT present in the beans.

Rolled up banknotes, hollowed-out pens, cut straws, pointed ends of keys, specialized spoons, long fingernails, and (clean) tampon applicators are often used to insufflate cocaine.

Drug dealers selling heroin to users who inject dilute the drug with different products from dealers selling to users who smoke or insufflate the drug; diluents which can easily form a solution with water for injecting heroin can be problematic for users who are sniffing the powder.

They handed a trumpet to the old man, who put it to the lips of the two creatures still suspended in their vegetable lethargy, their sweet animal sleep, and he began to insufflate soul into their bodies...The room filled with light; the light dimmed to a half-light, then to a darkness broken by orange flashes.