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At least some of the hypoxanthine is converted into uric acid by the parasite.
Hypoxanthine is oxidized to xanthine and finally to uric acid.
Hypoxanthine is also a spontaneous deamination product of adenine.
It is prone to deamination by adenosine deaminase to a hypoxanthine.
This transport system carries hypoxanthine, inosine and adenosine into the parasite.
It is created from hypoxanthine by xanthine oxidoreductase.
He is also credited with the discoveries of inositol and the purine derivative known as hypoxanthine.
Deamination of adenine results in the formation of hypoxanthine.
Hypoxanthine is a naturally occurring purine derivative.
A derivative of hypoxanthine was subsequently shown by others to be the key product of purine biosynthesis.
It is the ribonucleotide of hypoxanthine and the first nucleotide formed during the synthesis of purine.
Hypoxanthine is produced from adenine, xanthine from guanine.
Deaminated bases: hypoxanthine formed from deamination of adenine.
Hypoxanthine is a necessary additive in certain cell, bacteria, and parasite cultures as a substrate and nitrogen source.
Xanthine oxidase will degrade hypoxanthine to xanthine and then to uric acid.
Another origin of hydrogen peroxide is the degradation of adenosine monophosphate which yields hypoxanthine.
It is an analog of hypoxanthine that is hydroxylated by xanthine oxireductase at the 2-position to give oxipurinol.
Foods high in the purines adenine and hypoxanthine may be more potent in exacerbating hyperuricemia.
In prolonged ischemia (60 minutes or more), hypoxanthine is formed as breakdown product of ATP metabolism.
However, more frequently in purine degradation, xanthine is formed from reduction of hypoxanthine by xanthine oxidoreductase.
Purine nucleoside phosphorylase intraconverts inosine and hypoxanthine.
The selective culture medium is called HAT medium because it contains hypoxanthine, aminopterin, and thymidine.
The parasite is unable to synthesize purines (including adenosine, hypoxanthine and adenine) and must take these up from the host.
The rate of adenosine uptake was greater than the rate of hypoxanthine uptake in infected human red blood cells.
It differs from other nucleoside analogues, because it does not have any of the regular bases, instead it has hypoxanthine attached to the sugar ring.