Administering hypodermoclysis at two sites for faster fluid uptake is a technique still in use today.

These included asbestos bandages, mica windows for brain surgery, and multiple site hypodermoclysis.

Hypodermoclysis can be used where a slow rate of fluid uptake is required compared to intravenous infusion.

Normal hypodermoclysis would be too slow in emergency conditions, but Kane's invention speeded up the rate of fluid replacement many times.

Hyalase can improve absorption via hypodermoclysis.

"Simple device for rapid hypodermoclysis in combating shock", Journal of the American Medical Association, vol.34, no.9, pp.

The chief advantages of hypodermoclysis over intravenous infusion is that it is cheap and can be administered by non-medical personnel with minimal supervision.

Fluids can be replaced via oral administration (drinking), intravenous administration, rectally, or by hypodermoclysis, the direct injection of fluid into the subcutaneous tissue.

Parenteral fluids, delivered either intravenously or subcutaneously by hypodermoclysis, are sometimes considered, particularly when the goal is to reverse delirium [ 85 ] .

It also increases the absorption rate of parenteral fluids given by hypodermoclysis, and is an adjunct in subcutaneous urography for improving resorption of radiopaque agents.

Potential interventions for fever management include primary interventions directed at the underlying cause, hydration with parenteral fluids or by hypodermoclysis, nutritional support, and nonspecific palliative measures.

Prior to fluids or medicines being given intravenously, the Murphy drip and hypodermoclysis were the prime routes to administer fluids such as for replacement when patients could not be fed by mouth.