Achlorhydria and hypochlorhydria is when there is very little, or no gastric acid in the stomach.

If therapeutic hypochlorhydria is carcinogenic to the stomach, gastric cancer associated with cimetidine use in 1977 should only begin to appear by now.

Taylor suggests that in more than 50% of cases of acute H pylori infection, hypochlorhydria lasts for several weeks.

Effect of hypochlorhydria due to omeprazole treatment or atrophic gastritis on protein-bound vitamin B12 absorption.

Having too little or no gastric acid is known as hypochlorhydria or achlorhydria respectively and are conditions which can have negative health impacts.

In autoimmune gastritis, the immune system attacks the parietal cells leading to hypochlorhydria (low stomach acidity).

Hypochlorhydria induces G Cell (Gastrin producing) hyperplasia, which leads to hypergastrinemia.

H pylori has been shown to produce a factor which inhibits parietal cells in vitro and hypochlorhydria may be a feature of the acute infection.

Chronic alcoholic patients may have normal, enhanced, or diminished acid secretory capacity; hypochlorhydria being associated histologically with atrophic gastritis.

The autoimmune response subsequently leads to the destruction of parietal cells, which leads to profound hypochlorhydria (and elevated gastrin levels).

Hypochlorhydria from short-term omeprazole treatment does not inhibit intestinal absorption of calcium, phosphorus, magnesium, or zinc from food in humans.

Atrophic gastritis and superficial gastritis were more often seen in the alcoholic patients, which accounted for the hypochlorhydria seen in a group of these patients.

In hypochlorhydria and achlorhydria, there is low or no gastric acid in the stomach, potentially leading to problems as the disinfectant properties of the gastric lumen are decreased.

It has been shown that the therapeutic hypochlorhydria which is the primary action of these drugs is associated with increased gastric bacterial growth, reduction of nitrate to nitrite, and increased concentration of carcinogenic N-nitroso compounds in the gastric juice.

The lack of stomach acid, also called hypochlorhydria, is the lack of sufficient hydrochloric acid, HCl, which is required for the digestion of proteins and the absorption of nutrients, particularly of vitamin B and of calcium.