hypertrichosis lanuginosa

Acquired hypertrichosis lanuginosa is commonly present with cancer.

One record in history concerning congenital hypertrichosis lanuginosa is the hairy family of Burma, a four-generational pedigree of the disease.

She was born with a genetic condition called hypertrichosis terminalis (or generalized hypertrichosis lanuginosa); that is, her face and body were covered with straight black hair.

Hypertrichosis lanuginosa Acquired hypertrichosis lanuginosa is characterized by rapid growth of lanugo hair, particularly on the face.

Hypertrichosis lanuginosa Congenital hypertrichosis lanuginosa is noticeable at birth, with the infant completely covered in thin lanugo hair.

Congenital hypertrichosis lanuginosa may be caused by a mutation on the 8q chromosome; however, it could also be possibly the result of a spontaneous genetic mutation rather than inheritance.

In normal circumstances, lanugo hair is shed before birth and replaced by vellus hair; however, in a person with congenital hypertrichosis lanuginosa, the lanugo hair remains after birth.

Originally, she was believed to have congenital hypertrichosis lanuginosa; however, the generalized form of the syndrome coupled with her gingival hyperlasia indicated that her condition was congenital terminal hypertrichosis.

Only 50 cases of congenital hypertrichosis lanuginosa have been recorded since the Middle Ages, and fewer than 100 cases of congenital generalized hypertrichosis have been documented in scientific publications and by the media.

In some cases, paraneoplastic acanthosis nigricans (35% of patients), Florid cutaneous papillomatosis, Ichthyosis acquisita (Acquired hypertrichosis lanuginosa), Cowden syndrome, Tylosis, Acrokeratosis paraneoplastica of Bazex and Tripe palms accompanies the sign of Leser-Trélat.