Another man who suffered from hyperpathia and reduced nerve functioning later experienced referred itch in conjunction with his pathology.

CPSP can also lead to a heightened central response to painful sensations, or hyperpathia.

Specific features of the neurologic examination such as altered sensation (hypoesthesia, hyperesthesia, hyperpathia, allodynia) in a painful area are suggestive of neuropathic pain.

Hyperpathia describes the neuropathic pain which the pain threshold on one hand is elevated and the other hand is central hyperexcited whenever there is a loss of fibres.

The International Association of the Study of Pain's (IASP) definition of hyperpathia is that: A painful syndrome characterized by an abnormally painful reaction to a stimulus, especially a repetitive stimulus, as well as an increased threshold.