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Regression of the hyaloid artery leaves a clear central zone through the vitreous humor, called the hyaloid canal or Cloquet's canal.
Occasionally, failure of the normal third trimester gestational atrophy of the hyaloid canal and the tunica vasculosa lentis is associated with other anomalies.
Hyaloid canal is a small transparent canal running through the vitreous body from the optical nerve disc to the lens; in the fetus it contains a prolongation of the central artery of the retina, the hyaloid artery.