A specific function for the gyrus rectus has not yet been brought to light.

As illustrated in Brodmann-10, It constitutes most of the orbital gyri, gyrus rectus and the most rostral portion of the superior frontal gyrus.

The terminal nerve appears just ahead of the other cranial nerves bilaterally as a microscopic plexus of unmyelinated peripheral nerve fascicles in the subarachnoid space that covers gyrus rectus.

Orbital part: Lateral orbital gyrus, anterior orbital gyrus, posterior orbital gyrus, medial orbital gyrus, gyrus rectus.

The portion of the frontal lobe medial to the medial orbital gyrus is named the gyrus rectus (or straight gyrus), and is continuous with the superior frontal gyrus on the medial surface.

Recent meta-analyses of neuroimaging studies in major depression, reported that compared to controls, depressed patients had increased volume of the lateral ventricles and adrenal gland and smaller volumes of the basal ganglia, thalamus, hippocampus, and frontal lobe (including the orbitofrontal cortex and gyrus rectus).