Responses are organized based upon the particular form needed to fit the current environmental challenges as well as the functional consequences.

The functional consequences of these mutations are unknown.

This implies important functional consequences for oxygen affinity.

Necessary for the maturation of many proteins, processing can also occur afterwards, often resulting in dramatic functional consequences.

"Functional consequences of immune cell adhesion to endothelial cells".

The primary feature is recurrent episodes of depersonalization and/or derealization that have functional consequences.

To date the functional consequences of Siah1a association with group I mGluRs are unknown.

While PIM kinase to autophosphorylate, the functional consequences are not known.

This condition, known as septal rupture, leads to significant deformations of the lung architecture (video) that have important functional consequences.

In a second part of the study, the team tried to interpret the functional consequences of changes in gene expression observed in the microarray analysis.

The functional consequences include diminished epidermal adhesion and skin blistering in response to minimal shearing forces .

Early tools using phylogenetic and structural information have shown promise in predicting the functional consequences of a mutation [ 13 ] .

To date, the functional consequences of DNA-PK-mediated transcription factor phosphorylation are not known.

Minireview: parathyroid hormone-related protein as an intracrine factor--trafficking mechanisms and functional consequences.

This redistribution has important functional consequences: conduction across the axon is re-established, but the speed of conduction is reduced.

Further studies will be needed to determine if group I mGluRs and Siah1a interact physiologically, and whether this interaction has functional consequences.

This sequence diversity can have important functional consequences as the affinity between regulatory proteins and their binding sites is modulated by changes in binding-site sequence [ 1].

In addition, it was shown that it was the performance of burrowing behaviour that was important to the mice, not simply the functional consequences of the behaviour.

RSS variability has important functional consequences: the efficiency with which each RSS mediates recombination depends on its sequence [ 46].

The ability of PTPrho to dephosphorylate BCR was shown to have functional consequences for the normal development of neuronal dendritic arborization.

If at least some of the NGF-promoted alterations in RP transcript abundance lead to changes in expression of the corresponding proteins, what might be the functional consequences?

Of the mutations with known functional consequences, 4 produce channels that are either completely non-functional, and two that result in channels which open at far more hyperpolarized potentials than wild-type.

Proper variant descriptions are expected to facilitate searches for more information about the functional consequences in the literature and in gene variant or locus-specific databases (LSDBs).

The robust approach to sequencing the complete coding region (exome) has the potential to be clinically relevant in genetic diagnosis due to current understanding of functional consequences in sequence variation.