The words burst from the page, "Multiple filling defects consistent with tumor."

Any mass filling defects (embolus or other matter such as fat) appears darker.

Barium meal showed a filling defect in the prepyloric region.

In leiomyoma, there is smooth filling defect.

In esophageal cancer, it shows a characteristic filling defect ("Rat-tail" deformity).

Air can also be accidentally instilled in to the uterine cavity by the operator, thus limiting the exam due to iatrogenically induced filling defects.

Any mass filling defects, such as an embolus, will appear dark in place of the contrast, filling/blocking the space where blood should be flowing into the lungs.

Contrast-enhanced CT scan may reveal underlying sinusitis, thickening of the superior ophthalmic vein, and irregular filling defects within the cavernous sinus; however, findings may be normal early in the disease course.

Reasons for performing a retrograde pyelogram include identification of filling defects (e.g. stones or tumors), as an adjunct during the placement of ureteral stents or ureteroscopy, or to delineate renal anatomy in preparation for surgery.

Stone recurrences in five patients are believed to be the result of residual stones as they reformed by the six month follow up examination and each of the post procedure contrast studies had shown a filling defect in the neck of the gall bladder or cystic duct.