Immunoblots were performed and confirmed that survivin does not inhibit by mechanism of preventing Bax or Fas protein from being made into fully functional proteins.

Another intriguing aspect of this patent is that for LS9 to employ it, they must bypass using FAS proteins which have been patented by other components.

If exon 6 is skipped, the resulting mRNA encodes a soluble Fas protein that does not promote apoptosis.

Apoptosis and adenocarcinoma of the cardia: expression of p53, Bcl-2, Bcl-XL, WAF1, and fas proteins and association with characteristics of the tumors.

The mature Fas protein has 319 amino acids, has a predicted molecular weight of 48 kiloDaltons and is divided into 3 domains: an extracellular domain, a transmembrane domain, and a cytoplasmic domain.