The following hereditary disorders of the muscle energy supply may cause recurrent and usually exertional rhabdomyolysis:

Diseases which sometimes cause symptoms which appear similar to colic include laminitis and exertional rhabdomyolysis.

Equine Exertional Rhabdomyolysis (ER, "tying up")

Equine exertional rhabdomyolysis (ER, also known as tying up, azoturia, or Monday morning disease) is a syndrome that damages the muscle tissue in horses.

Following an HYPP attack, the horse appears normal and is not in any pain which helps to distinguish it from Equine Exertional Rhabdomyolysis (ER), commonly known as "Azoturia," "Monday Morning Sickness" or "tying up."

Of these, some cause isolated attacks of rhabdomyolysis (e.g. dietary deficiency in vitamin E and selenium, poisoning associated with pasture or agricultural poisons such as organophosphates), while others predispose to exertional rhabdomyolysis (e.g. the hereditary condition equine polysaccharide storage myopathy).