"Mapping and assessment of epileptogenic foci using frequency-entropy templates".

Excitotoxicity is a possible factor in the development of PTE; it may lead to the formation of a chronic epileptogenic focus.

People whose PTE does not respond to medication may undergo surgery to remove the epileptogenic focus, the part of the brain that is causing the seizures.

Many causes of the epilepsy have been theorized, with EEG often finding the hamartoma itself as the source of electrical activity, or epileptogenic focus.

Currently, the only manner to acquire the signal for study is through the use of patients requiring invasive monitoring for localization and resection of an epileptogenic focus.

FocusDET: Accurate localization of epileptogenic foci in intractable partial epilepsy is essential for assessing the possibility of surgery as a treatment.

This is usually reserved for cases in which complex or grand mal seizures are produced by an epileptogenic focus on one side of the brain, causing an interhemispheric electrical storm.

Current research on this topic is aimed at improving the technique in order to increase success rates as well as developing non-invasive forms of physiologic monitoring in order to determine the epileptogenic focus conclusively.

A specific software package was developed to locate the epileptogenic focus using Ictal and Inter-ictal SPECT images and MRI employing the SISCOM methodology.