Cholecystitis usually presents as a pain in the right upper quadrant or epigastric region.

Pain in the foregut is typically referred to the epigastric region, just below the intersection of the ribs.

The epigastrium (or epigastric region) is the upper central region of the abdomen.

Pain from the region will be referred to the epigastric region of the abdomen due to its associated dermatomes.

"Chaussier's sign": Severe pain in the epigastric region, a premonitory symptom of eclampsia.

About 25-50% of hepatic adenomas cause pain in the right upper quadrant or epigastric region of the abdomen.

Also, severe pain in the epigastric region is experienced by the patient along with bloating in the epigastric and umbilical regions.

The pain may be referred pain that is felt in the right scapula rather than the right upper quadrant or epigastric region (Boas' sign).

During breathing the diaphragm contracts and flattens, displacing the viscera and producing an outward movement of the upper abdominal wall (epigastric region).

Venous hum heard in epigastric region (on examination by stethoscope) because of collateral connections between portal system and the periumbilical veins in portal hypertension.

From the history given, the appearance of pain in the epigastric region or around the stomach at the beginning of disease with a subsequent shift to the right iliac region.

His name is also associated with Auenbrugger's sign, a bulging of the epigastric region in the thorax, in cases of large effusions of the pericardium, the membrane which envelops the heart.

Therefore, the epigastric region is not a muscle nor is it an organ, but it is a zone of activity where the actions of the rectus abdominus and the diaphragm produce an outward bulging of the upper abdominal wall.