downregulate

Every time we tried to downregulate a gene with existing technologies, the cell would change.

Use of long-acting agonists will downregulate the receptor population.

This interaction can either upregulate or downregulate transcription.

However, eventually most of these cells downregulate their regulatory capabilities and become effector cells.

When bacterial cells run out of nutrients, they enter stationary phase and downregulate protein synthesis.

Exercise, an example of response modulation, can be used to downregulate the physiological and experiential effects of negative emotions.

If c-Src is indeed a factor in the development of some colon tumors then it would be advantageous to develop techniques to downregulate its expression.

It was also shown that they upregulate the transcription from the p40 promoter (mentioned below), but downregulate both p5 and p19 promoters.

These cells generally suppress or downregulate induction and proliferation of effector T cells.

Epidermal growth factor and transforming growth factor a downregulate human gastric gene expression.

Traditional Chinese herbal medicines, like berberine downregulate E-selectin.

The basolateral calcium-sensing receptor has the ability to downregulate the activity of this transporter upon activation.

Evidence suggests that phytoplasmas downregulate a gene involved in petal formation, instead causing leaves or leaflike structures to form.

Therefore, one way in which exercise induces an increase in muscle mass is to downregulate the pathways which have the opposite effect.

GnRH agonists can be used to "downregulate" pituitary function and control reproductive function.

This indicates that, in flies, precursors express Delta and that those specified for neuroblast development downregulate its expression.

Dietary interventions and modifications such as vegan diets shown to downregulate IGF-1 activity, has been associated with lower risk of cancer.

"In contrast to small-molecule inhibitor drugs that can target only about 10% of the human genome, this approach could downregulate most human genes," Wee says.

To date, numerous experiments in animal models suggest RNAi can downregulate a variety of target genes effectively.

Specifically, positive, good-natured humor has been shown to effectively upregulate positive emotion and downregulate negative emotion.

Besides, hepcidin seems to downregulate both TFR1 and DMT1 through an unknown mechanism.

Vitamin D and analogs are used to downregulate the cutaneous immune system and epithelial proliferation while promoting differentiation.

In critical gonadal stages, between six and nine weeks after fertilization, the ovaries upregulate it while the testes downregulate it.

Novel research has identified a microRNA that is able to downregulate CCR6 in cancer cell lines.

ADRBK1 can downregulate response to epinephrine